IFNG and neoplasm: These DC (or control DC that were pulsed but had not been irradiated) were use to vaccinate mice; 10 days after the last vaccination the mice were challenged with B-16A2/Kb tumor, it was found that mice in the group treated with the DC that had been irradiated had better survival, and a higher induced immunity as measured by IFN-γ production in an ELISPOT assay with the MART-127-35 peptide (Liao et al., 2004).