C3 and Thiamine deficiency: Furthermore, Complement component 3 (C3), another inflammation-related gene, was found to be up-regulated in the IC in thiamin deficiency animals (Vemuganti et al., 2006) and in our ablated animals; supporting the idea of an ongoing inflammatory process at 15 days post-lesion which is stronger in the ipsilateral IC, accordingly with a heaviest preterminal fields degeneration after cortical ablation in the ipsilateral IC rather than the contralateral (Feliciano and Potashner, 1995).