In this study, we genotyped five p21 SNPs (rs1801270 at codon 31, rs762623 and rs2395655 in the promoter region, rs3176352 in an intron, and rs1059234 in the 3’ non-coding region) in 393 cervical cancer patients and 434 cancer-free controls to look for any associations between SNP alleles or genotypes and cervical cancer in a Chinese population. Here, CDKN1A is linked to cancer.