As noted above, CXCL13 is found in TLOs, including those associated with Helicobacter pylori (Mazzucchelli et al., 1999), rheumatoid arthritis (Loetscher and Moser, 2002), Sjögren’s syndrome (Barone et al., 2005), inflammatory transgenes (Kratz et al., 1996; Hjelmstrom et al., 2000; Drayton et al., 2003), and cancer (Bergomas et al., 2012). This evidence concerns the gene CXCL13 and rheumatoid arthritis.