Adipose tissue produces several proteins (adipocytokines), such as TNF-alpha, IL-6, type-1 plasminogen activator inhibitor (PAI-1), adiponectin, leptin, resistin, visfatin and apelin are associated with the risk of cancer at various sites (e.g., breast, prostate gland, endometrium and colorectum) (8-11). This evidence concerns the gene NAMPT and cancer.