ZAP70 and chronic myelogenous leukemia, BCR-ABL1 positive: When the expression level of the TCRζ, FcεRIγ, ASF/SF-2 and ZAP-70 genes was compared between both groups, a significantly higher level of ASF/SF-2 and FcεRIγ gene expression was found in the WT+AS-CML group (p = 0.014, p = 0.005), and the level of TCRζ and ZAP-70 gene expression was approximately two-fold higher in the WT+AS-CML group; however, there was no significant difference in the expression of thses genes when compared with the WT+AS+CML group (p = 0.319, p = 0.261) (Figure 5).