The expression correlation of the TCRζ and ZAP-70 genes was analyzed, and a significant positive correlation was found in the healthy control, CML-CR and CML groups (r = 0.600, p = 0.023; r = 0.637, p = 0.001; and r = 0.460, p = 0.003, respectively). The gene discussed is ZAP70; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.