Recently, we has reported the expression pattern of the four CD3 genes in patients with AML and CML[2,4,5,15], and it has been reported that the aberrant TCRζ chain expression found in the T cells of patients with systemic lupus erythematosus (SLE) may be associated with the decreased stability and translation of a TCRζ mRNA with an alternatively spliced 3'-untranslated region[16]. The gene discussed is CD247; the disease is systemic lupus erythematosus.