The expression of the TCRζ gene in the CML group was significantly lower than that in the healthy control and CML-CR groups (p = 0.027,p < 0.001), while a significantly higher level of FceRIγ (p = 0.001, p < 0.001) and ASF/SF-2(p = 0.002, p < 0.001) gene expression was found in the CML chronic phase (CML-CP) group. This evidence concerns the gene CD247 and chronic myelogenous leukemia, BCR-ABL1 positive.