Notably, resveratrol, a natural phytoalexin antioxidant found in grapes and red wine, known to induce mitochondrial biogenesis and protect against atherosclerosis in animal models[23,25], increased cholesterol efflux to apoA-I, at concentrations around 20-30 μM, as previously described[22,24]. This evidence concerns the gene APOA1 and atherosclerosis.