CALR and toxoplasmosis: These included a peripheral smear, clotting tests, serology for infectious agents such as EBV, CMV, HIV, toxoplasmosis, erythrocyte sedimentation rate (ESR), c-reactive protein level, liver function tests, direct Coombs test, C3 and C4 levels, serum protein electrophoresis, and an autoimmune screen, including antinuclear antibodies (ANA), anti-dsDNA antibodies, anti-SSA/Ro and anti-SSB/La antibodies, and antiphospholipid antibodies.