CHI3L1 and neoplasm: The estimated mean survival time of patients with positive YKL-40 intratumoral expression was 55.13 months (95% CI: 49.69 to 60.58 months) whereas that of patients with negative tumor tissue was significantly longer at 65.78 months (95% CI: 60.17 to 71.40 months; P = 0.017 as determined by the Log-rank test) (Figure 3).