Alanine Aminotransferase(ALT), Aspertate Aminotransferase(AST), alkaline phosphatase(ALP) and gamma-glutamyl transpeptidase(GGT) were analyzed and all of them increased in HCC than in LC, but only ALT and GGT increased significantly(P<0.05) in HCC than in LC( Table 1). The gene discussed is GGTLC1; the disease is hepatocellular carcinoma.