Also important was the observation that the genes coding for several proteins overexpressed in tumors (both MA and LA) have been mapped to 11q13 (CFL1, GSTP1, SERPINH1) and 8q23-24 (EEF1D, RPL8), which are chromosome segments frequently amplified in head and neck carcinomas and may be related to the progression of the disease [30], [31]. Here, CFL1 is linked to head and neck carcinoma.