Although there are hundreds of differentially-expressed genes in diabetic heart and DDRG at different time points in the course of the disease, four co-differentially-expressed genes (Gadd45α, Ada, Scn7a, and Txnip) were ultimately identified by intersection analysis between DDRG and DCM in all marked time points. Here, SCN7A is linked to familial dilated cardiomyopathy.