This prevalence was of the same order of magnitude as previously reported in SLE and APS patients [10–13], and in this work, the authors retrieved a significant association between anti-apoA-1 IgG and serum amyloid A (SAA) protein, a multifunctional protein located at the crossroad of inflammation, cholesterol homeostasis, and atherogenesis [23, 24]. This evidence concerns the gene APOA1 and systemic lupus erythematosus.