TYK2 and systemic lupus erythematosus: The TYK2 SNP rs2304256, was found to be associated with SLE in a Scandinavian cohort (P = 5.6 × 10−6) [13], but not associated with SLE in a UK cohort [42], however this same UK study also found another TYK2 SNP, rs12720270, associated with SLE that was not found within the Scandinavian cohort (P = 0.004).