Increased ROS bioavailability, decreased antioxidant capacity, or both occur in many models of hypertension such as SHR (Suzuki et al., 1995), Dahl salt-sensitive (Swei et al., 1997), AngII-infused rats (Laursen et al., 1997), renal hypertensive 2K-1C (Rodrigues et al., 2008), and human hypertension (Vaziri, 2004). Here, AGT is linked to Hypertension.