Similar effects have been described for the selective M3 receptor antagonist bencycloquidium bromide, which inhibited ovalbumin-induced mRNA expression of IL-5, IL-4, and MMP-9, as well as lung tissue eosinophil infiltration, airway mucus production, and collagen deposition in lung tissues in a murine asthma model [71]. The gene discussed is MMP9; the disease is asthma.