Interestingly, a ChIP-chip array study of MYCN/c-MYC target genes in neuroblastoma demonstrated that distinct MYCN/c-MYC target gene expression was associated with overall survival, and independent of well-established markers such as MYCN amplification, disease stage, and age at diagnosis (Westermann et al., 2008). The gene discussed is MYC; the disease is neuroblastoma.