TP53 and neuroblastoma: In contrast, a number of studies including our own have reported predominantly nuclear localization and/or functional p53 in neuroblastoma (Layfield et al., 1995; Hoehner et al., 1997; Danks et al., 1998; Isaacs et al., 1998; McKenzie et al., 1999; Smart et al., 1999; Keshelava et al., 2000, 2001; Tweddle et al., 2001a,b; Cui et al., 2002; Goldschneider et al., 2004; Chen et al., 2007, 2010; Xue et al., 2007; Kurata et al., 2008; Van Maerken et al., 2011; Gamble et al., 2012).