APLN and coronary artery disorder: In males, low-penetrance haplotype A-G (in order of rs56204867 and rs3761581) in apelin gene was significantly overrepresented in controls (1.73%) relative to CAD patients (0.4%) (P = 0.047), whereas haplotype A-T was marginally higher in patients (65.42%) than in controls (59.11%) (P = 0.061) (Table 3).