IL4 and Autoimmunity: Also at week 36, the profile of cytokine production by stimulated splenocytes from these mice was consistent with autoimmunity promotion, with an increased production of type Th1 (IL-2) and Th17 (IL-17) cell cytokines, and fundamentally, a reduced production of type Th2 cell cytokines (IL-4, IL-5, IL-10, and IL-3) [19]–[22].