The concentration of almost every cytokine in the supernatant of splenocytes from both SLE and CT mice increased throughout the study, except for granulocyte macrophage-colony stimulating factor (GM-CSF), interleukin (IL) -3, IL-12, IL-17, keratinocyte-derived cytokine (KC), and monocyte chemotactic protein-1 (MCP-1) (data not shown). Here, CALCA is linked to systemic lupus erythematosus.