Despite this reduction, the percentage of CD4+CD25+ T cells was increased at week 8 (x1.4 fold vs CT values, Figure 2C), and the percentage of CD4+CD25+FoxP3 T cells increased in SLE mice at week 8 (x1.4 fold vs CT values) and 16 (x1.16 fold vs CT values) (Figure 2D). The gene discussed is FOXP3; the disease is systemic lupus erythematosus.