Many studies have reported the involvement of ABC proteins in ATP release [21]–[23]: CFTR-regulated ATP release has been observed in a variety of native cell types, including erythrocytes and epithelial cells [24], [25], whilst transfection of carcinoma cells with CFTR or reconstitution of CFTR into lipid bilayers is associated with the appearance cAMP-dependent ATP release [26]–[28]. This evidence concerns the gene CFTR and carcinoma.