So far individual assays for some of these polymorphisms have been established by researchers, e.g., for CYP3A (Justenhoven et al., 2010; The MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk, 2010), CYP2D6 (Schaeffeler et al., 2003; Morike et al., 2008), CYP2C19 (Justenhoven et al., 2012), GST, UGT, and SULT1A (The MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk, 2010) as well as companies (e.g., Applied Biosystems and Third Wave Technologies)1,.2 The gene discussed is CYP3A4; the disease is breast carcinoma.