Lp-PLA2 mass (measured as a one standard deviation increase above mean) was not found to be associated with an increased risk of dementia (HR 0.98; CI 0.84 to 1.15) or AD (HR 0.98; CI 0.82 to 1.18) in the Framingham Study, however [6]. This evidence concerns the gene PLA2G7 and dementia.