For example, Erel et al. showed that AA response to ACTH was similar between women with PCOS and controls[27], whereas Kamel et al. reported that PCOS patients (n = 29) had higher basal and stimulated DHEAS, 17-OHP and stimulated F levels than idiopathic hirsutism (IH) (n = 21) and control (n = 20) subjects[28]. Here, POMC is linked to isolated hemihyperplasia.