In contrast, circulating proteins are more stable than RNA in blood and serum with several individual markers identified previously as prospective biomarkers for the presence of atherosclerosis, myocardial infarction, heart failure, or markers of pathways involved in these cardiac conditions such as inflammation, thrombosis, plaque stability, and oxidative stress, for example, troponin C, pro-brain natriuretic peptide (BNP) and C-reactive protein (CRP) [10,11]. The gene discussed is CRP; the disease is heart failure.