There was also no association between CD133 expression and clinical parameters such as lymph node metastasis (pooled OR = 1.16, 95% CI: 0.87–1.54, Z = 1.05, P = 0.315 fixed-effect) (Figure 3) or lymphatic invasion (pooled OR = 1.08, 95% CI: 0.81–1.43, Z = 0.53, P = 0.594 fixed-effect) (Figure 4). This evidence concerns the gene PROM1 and metastatic malignant neoplasm in the lymph nodes.