CDH17 and neoplasm: The mouse mammary carcinoma model that we have previously used to study the expression of cadherins [7] utilizes tumor cell lines that represent different stages of tumor progression: Ep5 cells are tumorigenic mammary epithelial cells transformed by the v-Ha-Ras oncogene, whereas Ep5ExTu cells, isolated from Ep5 cell tumors grown in mice, have undergone EMT in vivo and present a mesenchymal, invasive and angiogenic phenotype [25,26].