NFKB1 and colorectal carcinoma: For example, the NFKB1 -94ins/del del-allele was associated with risk of CRC among Swedes [odds ratio (OR) 3.81, 95% confidence interval (95% CI) 2.17–18.43, P < 0.0001 for heterozygous del-carriers and OR: 4.65, 95% CI: 2.43–8.89, P < 0.0001 for homozygous del-carriers], whereas no association was found among Chinese.47 An explanation for this apparent discrepancy may be suggested by the interaction between meat and NFKB1 -94ins/del polymorphism found in the Danish cohort.21 Among NFKB1 -94ins/del variant allele carriers, risk of CRC depends on meat intake.