To conclude, prospective studies suggest that dietary meat interact with NAT1, NAT2, ABCB1, NFKB1, but not HMOX1, ABCC2 or ABCG2, cruciferous vegetables with GSTM1, GSTT1, and CCND1, calcium with VDR, vitamin C, vitamin E and carotene with MGTM, fibre with IL10, alcohol with PPARG, folate and alcohol with DNA methylation in relation to CRC. The gene discussed is NFKB1; the disease is colorectal carcinoma.