TLR2 and rheumatoid arthritis: As shown in Figure 4, HOMA index significantly correlated with fold increase of TLR2 expression (calculated as MFI) in monocytes of RA patients after stimulation with 10 μg/mL peptidoglycan (r = 0.441, P = 0.027, Figure 4(a)), while failing to reveal significant correlation in normal controls (r = 0.249, P = 0.492, Figure 4(b)).