Similarly, in CSS subjects with and without prior clinical cardiac manifestations the differences in the actual (0 (0–0) versus 0 (0–20), p = 0.24) and maximally measured MPO-ANCA titre at prior flare(s) [0 (0–0) vs 0 (0–30); p = 0.24] did not reach statistical significance. Here, MPO is linked to eosinophilic granulomatosis with polyangiitis.