BIRC6 and acute myeloid leukemia: Consistent with our data showing increased BIRC6 expression upon neutrophil differentiation of NB4 and HL60 AML cells, we observed a 3.3- and 2.8-fold increase in BIRC6 mRNA expression at day 3 and 6 upon in vitro granulocytic differentiation of CD34+ progenitor cells, respectively (data not shown).