Surprisingly, we found significantly lower BIRC6 levels in AML patients with the translocations t(8;21) and t(15;17) as well as in AML patients with a complex karyotype, whereas no significant differences in BIRC6 expression was found in AML patients with inv(16) or normal karyotype as compared to its expression levels in granulocytes from healthy donors (Figure 1). The gene discussed is BIRC6; the disease is acute myeloid leukemia.