IL10 and cutaneous leishmaniasis: For instance, we have shown that the S. mansoni antigens rSm29, rSmTSP-2, and PIII induce IL-10 and IL-5 production by PBMC of cutaneous leishmaniasis patients and that they are able to control the in vitro inflammatory response in a group of patients, independent of the clinical features, such as number and size of lesions [8].