IL1B and dengue disease: Overall, our results indicated that cytokines and chemokines associated with innate immune activity (e.g. IFN-γ, IP-10), Th2 cell response (IL-4, IL-10, and IL-13), inflammation (IL-1b, IL-6, and IL-8), chemotaxis of macrophages and neutrophils (Eotaxin, MIP-1b) are all maximally elevated in dengue patients during the early febrile phase.