Compared to subjects with homozygote CC at rs1501299, the subjects with homozygote AA had significantly higher adiponectin levels after adjusting for BMI and glucose levels (6.82±0.52 μg/ml vs. 5.85±0.57 μg/ml in controls, 9.13±0.49 μg/ml vs. 8.27±0.53 μg/ml in COPD patients, P<0.05 in both groups). Here, ADIPOQ is linked to chronic obstructive pulmonary disease.