In addition, the COPD patients showed a significantly lower BMI (22.03±2.27 kg/m2 vs. 23.91±2.48 kg/m2, p<0.01) and a 1.4-fold higher adiponectin levels (8.54±0.66 μg/ml vs 6.12±0.57 μg/ml; p<0.01). This evidence concerns the gene ADIPOQ and chronic obstructive pulmonary disease.