Based on prominent hyperactivity (Fig. 8A) and ataxia (Fig. 8C), as well as the small body size (Fig. 4B–C) and early post-natal death (Fig. 4A) of Mfsd2a KO mice, it is likely that MFSD2A plays a profound role in brain metabolism. This evidence concerns the gene MFSD2A and Ataxia.