We first detected the expressions of Kindlin-1 and Kindlin-2 as well as epithelial to mesenchymal transition (EMT) markers E-cadherin and Vimentin in lung cancer cell lines derived from SCC, AC and LCC and found that Kindlin-1 and Kindlin-2 were differentially expressed in lung cancer cell lines (Fig. 4b). Here, CDH1 is linked to leukoencephalopathy with calcifications and cysts.