41 Bennett Bennett KL KL ,  Lee Lee W W ,  Lamarre Lamarre E E ,  Zhang Zhang X X ,  Seth Seth R R ,  et al et al  ( 2010 2010 )  HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas . The gene discussed is SEPTIN9; the disease is head and neck squamous cell carcinoma.