Although we observed co-localization of the antisense foci with MBNL1 in human DM1 heart, we did not see clear co-localization with MBNL1 or MBNL2 in DMSXL heart and skeletal muscles, probably due to the low levels of antisense transcripts in the transgenic mice. This evidence concerns the gene MBNL2 and myotonic dystrophy type 1.