IL1B and skin infection: Furthermore, there was substantial DsRed fluorescence signal on day 1 during our in vivo S. aureus skin infection (Figs. 2 and 3) and at this time point we previously found that IL-1β was detected from the infected skin by ELISA and that both pro-IL-1β and cleaved IL-1β were detected by immunoblotting [11], [17].