Inflammasome activation and IL-1β signaling are important for immunity against several viruses including Influenza A, hepatitis B, Sendai and vesicular stomatitis virus (VSV) [24] and drive host responses that regulate cellular infiltration to sites of infection [32]–[35], adaptive immunity [23], [36] and direct viral control in combination with other host factors such as IFN-α/β (type I IFN), IFN-γ and TNF-α [21]–[22], [37]. Here, IL1B is linked to infection.