FH and hereditary leiomyomatosis and renal cell cancer: Third, although the children of the proband in pedigree 1 (two sons and one daughter; IV-1 to IV-3) showed no mutations of FH, the heat map assigned them to this HLRCC family and not to the non-cancerous control group, suggesting that we may not be discriminating HLRCC patients (III-4, III-9) from normal persons (IV-1 to IV-3), but may be separating families from each other.