AGT and pulmonary fibrosis: As renal and pulmonary fibrosis share similar features including fibrotic cytokines (ANGII, TGF-β) and ROS overproduction, and activated myofibroblasts originating from local mesenchymal cells, it can be speculated that enhanced PRMT1 expression may participate in the development of lung fibrosis by various mechanisms which may not necessarily have to be ADMA-dependent.