PRMT1 and pulmonary fibrosis: Enhanced PRMT1 expression may also affect the regulation of transcription as PRMT1 was found to co-activate the nuclear factor-κB (NF-κB) signaling pathway [92] that, under stimulatory conditions, may trigger expression of MMP1 [93], MMP2 [94], MMP9 [93,95], collagen I [96], all proteins that have been reported to be up-regulated in the lungs of IPF patients and animal models of pulmonary fibrosis [6].