Nearly all dermatofibrosarcoma protuberans carry a t(17;22)(q22;q13) chromosomal translocation, which fuses the COL1A1 gene on chromosome 17 to PDGFB on chromosome 22, and result in a chimeric COL1A1-PDGFB protein[18]. The gene discussed is COL1A1; the disease is dermatofibrosarcoma protuberans.