GCG and type 2 diabetes mellitus: A more recent study comparing both of the above therapies given for eight weeks in patients with T2DM (baseline hemoglobin A1c (HbA1c) of 8.3 ± 1.0% and body mass index of 35 ± 5 kg/m2) revealed a reduction in postprandial glucagon secretion and an improvement in a homeostasis model assessment of beta-cell function (HOMA-B) with exenatide 10 mcg bid as well as sitagliptin 100 mg daily; however, the improvement was significantly more in exenatide treated patients compared to the sitagliptin treated group [32].