The magnitude of p190-derived peptide-specific T cell response, as measured by the stimulation index, was the same in patients and healthy donors and was in the range of what we previously found in CML patients, confirming that ALL patients treated with TKIs maintain a functional and reactive immune system even against a poorly immunogenic self oncoprotein like p190. This evidence concerns the gene CNTNAP1 and chronic myelogenous leukemia, BCR-ABL1 positive.