TP53 and familial pancreatic carcinoma: They reported that p53 protein overexpression was observed in 67% of the samples with pancreatic cancer, but not in samples with chronic pancreatitis, and they found that by using the combination of p53 protein overexpression and conventional histological examination, the diagnosis of pancreatic cancers improved as follows: 90% sensitivity, 91% specificity, and 92% accuracy, whereas the conventional histological EUS-FNA diagnostic test statistics for the pancreatic masses were as follows: 76% sensitivity, 91% specificity, and 79% accuracy.