The overall data showed that the individuals who carried the GSTM1 null genotype had a significantly increased PCa risk compared with those who carried the GSTM1 present genotype in all subjects (OR = 1.2854, 95% CI = 1.1405–1.4487, P<0.0001, I2 = 69.69%, Fig. 2). The gene discussed is GSTM1; the disease is posterior cortical atrophy.