However, we did not find any differences in total CXCL10 mRNA or localization within the granulomas in WT and Lcn2KO M.tuberculosis-infected lungs during both early and chronic tuberculosis (data not shown).These novel data suggest that Lcn2 regulates some lymphocyte recruiting chemokines such as CXCL9, to constrain lymphocytic infiltration and granuloma formation during TB. The gene discussed is CXCL10; the disease is tuberculosis.