We also treated mouse 4T1 breast cancer cells with shRNA lentiviral particles targeting FGFR1-3.The silencing efficiency was not as high as in S115 cells, but nevertheless FGFR2 and FGFR3 silencing also resulted in increased FGFR1 gene expression in these cells. This evidence concerns the gene FGFR2 and breast carcinoma.