Except for the “Calcium Regulation in the Cardiac Cell” pathway, these pathways are expected to be involved in prostate cancer initiation, whereas the latter obviously is not involved in prostate carcinogenesis, but is composed of several sub-processes and regulators, such as the Na+/K+ATPase, the Na+/Ca2+exchanger, and regulators of G-protein signaling that might also be altered during prostate carcinogenesis. The gene discussed is SLC8A1; the disease is prostate carcinoma.