No fusion gene involving CDX1 has so far been described as opposed to another member of the Cdx family, CDX2. CDX2 is overexpressed in both lymphoid and myeloid leukaemias [29]–[31] and a fusion gene resulting from a balanced t(12;13) leading to an ETV6-CDX2 fusion was detected in a patient with acute myeloid leukaemia [32]. This evidence concerns the gene ETV6 and acute myeloid leukemia.